Integrative Cancer Management
Biomodulation:
This is aimed at decreasing the
tumor load through the use of the following:
1) Angiogenesis Inhibition: Angiogenesis
is the process through which cancer cells initiate blood
vessel proliferation in order to fuel rapid growth. Agents that interfere with
the formation of new blood vessels are an important part of a comprehensive
treatment strategy. Avastin is one example of conventional drugs that inhibit
angiogenesis, but with strong side effects. Other inhibitors are NSAIDs, frozen
shark cartilage extract (Comitris), curcumin, green tea, etc.
2) Poly MVA:
This compound is a non-toxic polynucleotide reductase. The MVA stands
for minerals, vitamins, and amino acids. LAPd stands for Lipoic acid /
Palladium complex. Lipoic acid is a natural powerful antioxidant that is
both water and fat soluble, which permits the Poly-MVA to pass across the cell
membranes and the blood brain barrier, which is impossible for most drugs,
including chemotherapy. When it enters cancer cells, protein radicals are
formed which denature the tumor cell’s proteins.
Since “normal cells” are capable of converting the radicals into energy and
water, no harm can occur. The original
human trials were done in Canada by the late oncologist, Dr. Rudy Falk, usually
in conjunction with standard chemotherapy and various other therapies. He
reported benefits including pain reduction or control, improved appetite and
weight gain, and increasing energy. Some patients are still using low doses of
Poly-MVA and have no signs of cancer after ten years of use. A recent study
presented at the American Academy for Anti-Aging Medicine (A4M) by an American
oncologist shows a 77% response rate of Stage IV cancer patients treated with
intravenous and oral Poly MVA.
3) Intravenous Vitamin C:
A growing number of studies in
vitro as well as in vivo suggest the use of high dose intravenous vitamin C as
an adjunctive therapy for cancer patients. Because of a relative catalase
deficiency in tumor cells, they are more susceptible to the effects of high-dose
ascorbate- induced peroxidation products. Concentrations of ascorbate high
enough to kill tumor cells can be achieved in humans.8
Addition of magnesium and
vitamin B6 does inhibit oxalate stone formation in stone formers. Patients
should also be screened for red blood cell G6PD deficiency to prevent
hemolysis. 9 Also, addition of other trace elements and minerals will
help provide nutrition to the normal cells deprived by the presence of cancer.
This will help increase the patient’s energy level.
4) Oxygenation Therapies:
The most fundamental feature
of a cancer cell is that it is relatively anaerobic. It needs sixty percent
less oxygen than a normal healthy cell. It does very poorly in the presence of
excess oxygen. All of this points toward oxidative therapy as a decent
treatment for cancer and a decent preventive measure as well. This includes ozone,
hydrogen peroxide, and hyperbaric oxygen.
Ozone, referred to as O3, is produced in a generator
using pure oxygen. In Major Auto Hemotherapy (MAH), blood is drawn,
mixed with ozone for few seconds and reinjected. The improvement in the immune
system is demonstrated by increased natural killer cell activity. In
vitro studies have shown that cancer cultures treated with ozone along with
5-FU did not develop resistance to chemotherapy, as did the untreated colonies.
This adjunctive therapy with chemotherapy and radiation therapy is further
enhanced if MAH is used at the same time with Ultraviolet Blood Irradiation
Therapy (UBIT).
5) Laetrile (B17):
Laetrile is a naturally
occurring substance in many foods. It has a large molecule which is made up of
2 parts of glucose, 1 part of Hydrogen Cyanide and 1 part of Benzaldehyde. The
last component gives it the pain relieving property. This big molecule is not
breakable in nature.
An enzyme Rhodanase, normally
present in our body, breaks the Hydrogen Cyanide component into Thycynate and
Benzaldehyde component into Benzoic Acid. Thyocynate and Bezoic acid are the
metabolic precursor pool for Vitamin B12 in our body.
An optimum level of Nutrients
is necessary for Laetrile to work. Zinc is especially significant in this
context. It is needed for the transport of Laetrile. High doses of Vitamin C
are synergistic to the action of Laetrile. Micro nutrients such as manganese,
magnesium, selenium, Vitamins B6, B9 and B12 are essential for optimizing the
effect of Laetrile. Vitamin A and Vitamin E help enhance metabolism. This is
why when given intravenously, Laetrile is mixed with Vit C and the other
minerals.
6) DCA:
Dichlor Acetic Acid or DCA is
a trace product of chlorinated water and chlorine containing chemicals. These
salts of DCA have been used to treat Lactic Acidosis.
A study published in 2007 at the
University of Alberta indicated its potential use in cancer. Later in that year
funding was secured to carry out a clinical trial of DCA in cancer patients.
Alberta local ethic committee and health Canada approved this trial.
DCA salts liberate Dichloracetate
ion which inhibits lactic Acid formation by suppressing the main enzyme in
Lactic Acid Cycle. The energy and respiration of cancer cells is compromised.
The cancer cells therefore are suffocated and ultimately die. 10
7) Hyperthermia:
It could be local, regional (part of body) or
whole body hyperthermia. It is a very popular and effective therapy in German
integrative cancer clinics. The main anti-cancer effects are achieved through
thermo-associated cytotoxic effects, angiogenesis inhibition, vascular
dilatation, and immunological effects.5
8) Vitamin D:
In February of 2006 a research
team led by Cedric F. Garland of the University of California at San Diego,
reported that vitamin D supplementation would reduce the occurrence of a wide
variety of cancers by 30-50%. 11
The geographical colon,
breast, ovarian and prostate cancer belt that encircles the world is in the
Northern latitudes. Cities like Seattle, Toronto, Boston, London, Dublin,
Helsinki, Copenhagen, Berlin, Moscow, Anchorage, fall within this global belt
and have high rates of these cancers. Recently it was reported that 1000-2000
IU of vitamin D, obtained from dietary supplements, sunlight exposure, or the
diet, would cut the risk of colon cancer in half.
Immunomodulation:
This includes all therapies that stimulate the immune system, improve
its cancer killing action, and prevent further cancer progression.
1) Low Dose
Naltrexone: LDN
Accumulating evidence suggests
that LDN can promote health supporting immune-modulation which may reduce
various oncogenic and inflammatory autoimmune processes.13 Most studies
have shown that naltrexone induces a two to three-fold increase in production
of metenkephalin, the endorphin that most specifically activates delta-opioid
receptors, the primary endorphin-related anti-growth factor on cancer cells. 14
. Endorphins raise the circulating levels of natural killer cells and
lymphocyte-activated CD-8 cells, the two immunological cell types that prevent
cancer by killing cancer cells as they arise.
2) Natural Killer cell stimulants: these
include AHCC, MGN III, IP6, NK Immune, etc.
3) Iscador:
Mistletoe induces tumor
necrosis, increases natural killer cell activity, increases production of
interleukins 1 and 6, activates macrophages, induces programmed cell death
(apoptosis), and protects DNA in normal cells during chemotherapy.
A German study done by Dr.
Ronald Grossarth-Maticek of the Institute for Preventive Medicine in Heidelberg
shows that, when used as adjunctive treatment in patients with a variety of
cancers, it can increase survival time by as much as 40%. Research indicates that mistletoe extract is most effective when
used in conjunction with conventional medical care for the treatment of solid
tumors such as breast cancer.
4) Wob-Mugos and Wobenzyme:
It is a formula containing several kinds of
hydrolytic, proteolytic enzymes from plant and animal sources that attack
cancer in several ways. First, it attacks the coating on tumor cells, which
disguises them from recognition by the immune system so that the antigens are
exposed. Second, it stimulates various components of the immune system such as
Natural Killer cells, T-cells and Tumor Necrosis factor. Third, it removes the
"sticky" coating on cancer cells that allow them to adhere to other
parts of the body; in effect, lessening the chances of metastasis.
Detoxification, Life Style and Diet Changes:
Removal of toxins (heavy metals, xenoestrogens, pesticides) from the
body, is considered as a very important part of the treatment. A variety
of approaches are used, including colon cleansing, fasting, chelation, water
therapy, heat therapy, and nutritional, herbal, and homeopathic methods. This
causes the liver to release stored up toxins into the digestive system to be
eliminated. Increasing water intake is another excellent way to get rid of
toxins in the body.
Likewise, it is very important to implement good nutrition, exercise,
and maintain emotional balance. Avoid preservatives, chemicals, coffee,
cigarettes, alcohol, red meats, and sugar. Your diet should be based on organic
whole grains, beans, juicing most raw vegetables, and some low sugar containing
fruits.
Body, Mind and Energy Therapies
These forms of therapies can
be applied to support behavioral patterns during recovery.
Many patients with chronic
illness or cancer mal-adapt to their situation and the brain becomes satisfied
with that level of function. Although it may not be the cause of the disorder,
it’s a
common cause for a patient’s poor response to biological treatment because
it can block the immune response. Meditation and Reiki are healing techniques
that help balance physical, mental and emotional energy flows. Reflexology stimulates
healing using pressure points on feet and hands.
1)http://www.cancer.ca/Canada-wide/About cancer/Cancer statistics
2) Journal
of Complementary and Integrative Medicine: 2008; Vol. 5: Issue. 1
3) Greenee H et al. Breast Cancer Research, Jan
31, 2009
4) http://www.rationaltherapeutics.com/physicians
5) Dieter & Migeod- Integrative Care - The German
Model, Cancer Guides II, June 2009.
6) 4th International Workshop on Hyaluronan in
Drug Delivery. Gressy, France, 1996.
7) J Control Release. 2008 Oct 6;131(1):64-9. Epub 2008 Jul 13
8) Clinical & Experimental experiences with Intravenous Vitamin C.
Bio- Communications research institute,
Wichita, Kansas, 67219.
9) RECNAC, Protocol for the
use of High Dose Intravenous Ascorbate as a Cytotoxic Chemotherapeutic.
10) Michelakis ED, Webster L, Mackey JR. Br J Cancer. 2008 Oct 7;99(7):989-94. Epub 2008 Sep 2.
11) American Journal Public
Health 96: 252-61, 2006
12) American Journal
Preventive Medicine 32: 210-16, 2007
13) Med Hypotheses. 2009 Mar;72(3):333-7. Epub 2008 Nov 28.
14)
http://www.lowdosenaltrexone.org/ldn_and_cancer.htm
